Hunting vigorously through the lazylaces archives for "point'n'click" unearthed the following results...
Solitude a plane crash on a tropical island is the way to go. As long as you can avoid the others that is [subbed by victoria].
Deep Chalk series continues in Deep Chalk (Third Phase) which is a 'gem' (hoho) of a game [subbed by victoria].
Somalia, or you're from the 18th century, then you'll be interested to know that not only is "Kidnapped By Pirates" your facebook status, but it's now also a point'n'click game... [subbed by Buji & victoria].
Phantasy Quest II, kind of like lost, but with less smoke monsters and polar bears, no crashed plane, and a total absence of that cad Benjamin Linus. In fact, not like lost at all, the island theme is the only connection, but at least this inane rambling stopping me singing "Let Me Be Your Phantasy" which was the alternative... [subbed & created by James]. Extra: Check out the original Phantasy Quest if you like this latest installment and you missed it first time around.
Bermuda Escape is set within the Bermuda Triangle so don't be surprised if your usual point'n'click skills go missing [subbed by anon].
point'n'click adventures of Mr. Seed in Regrowth. A very cool and mellow game for a Saturday, *nice* [subbed by charlie].
Gotta get up, gotta get up, gotta get up, to play Escape The Black Box.... a point'n'click horror game (so tread carefully with younger players and the squeamish). Now if you'll excuse me, I've got to go and answer the door, 1989 is here asking if it can have it's puns back... [subbed by victoria].
Sushi Room Escape [subbed by anon].
Loom Custody provide plenty of incentive for you to escape the room [subbed by Nymphaea].
walk like an Egyptian to play Alkirian 2: The Seven Scepters, but it helps... [subbed by anon].
Vorago at all costs. Hopefully everyone else (both of you), enjoys it though... [subbed by Daremaster Spoodle].
Cowboy Oddity is best played whilst performing some crazy dance moves and wearing your favorite tea cozy [subbed by anon].